Scientific studies have revealed body slim garcinia that several nutrients are able to effectively protect against endothelial dysfunction caused by atherogenic factors.
Unlike the conventional medicine approach to the treatment of atherosclerosis, which involves dealing with very few proven risk factors for heart disease, a comprehensive nutritional regimen can be used to address all of the risk factors that contribute to atherosclerosis.
Fatty Acids in Vascular Disease
Studies have shown that omega-3 fatty acids fight the development and progression of vascular disease through multiple mechanisms, including the reduction of triglycerides and blood pressure, improves endothelial function and increases in HDL cholesterol levels.
A research team examined the correlation between omega-3 fatty acid levels in the tissue and the circulating measurements of Lp-PLA2 , a marker of inflammatory arterial plaque, in more than 300 patients.
They found a strong, independent and inverse association between omega-3 tissue levels and the circulating marker Lp-PLA2. This led to the conclusion that the intake of omega-3 fatty acids may reduce Lp-PLA2 levels and thus reduce the risk of vascular disease .
In another study involving 563 elderly men, they were given 2.4 grams per day of omega-3 fatty acid supplements, resulting in a marked improvement in arterial elasticity.
In 16 patients with peripheral arterial disease who were already being treated with conventional methods, the addition of 2 grams of omega-3 fatty acids per day proved to significantly improve endothelial function.
Similarly, another study found that when omega-3 fatty acids were combined with rosuvastatin , the combination improves endothelium-dependent vasodilation, while rosuvastatin alone fails to improve endothelial function.
Propionyl L-carnitine (PLC)
The L-carnitine propionyl has drawn attention for its ability to directly improve endothelial function . Propionyl L-carnitine passes through the mitochondrial membrane to deliver L-carnitine directly to the mitochondria , the energy-producing organelles of the cells.
Carnitine is essential for the mitochondrial transport of fatty acids and energy production. 70 percent of the energy that burns the endothelial cells and the muscle cells of the heart comes from fatty acids, hence their importance.
By contrast, most other cells generate 70 percent of their energy from glucose and only 30 percent from fatty acids.
In human studies, propionyl L-carnitine significantly reduces homocysteine levels when given intravenously to hemodialysis patients.
Animal studies suggest that it may help prevent or lessen the severity of vascular disease.
In rabbits fed a diet high in cholesterol, which normally induces endothelial dysfunction and subsequent atherosclerosis, supplementation with that nutrient resulted in a reduction in plaque thickness, significantly lower triglyceride levels, and reduced cell proliferation foamy, distinctive cells of the lipid streak.
It also improves endothelial function by increasing the production of nitric oxide in animals with normal blood pressure and in animal models of hypertension.
The nitric oxideis important because it helps keep the arteries open. The increase in nitric oxide production induced by propionyl L-carnitine is related to its antioxidant properties, which results in a clear benefit for people suffering from vascular disease.
This amino acid has attracted attention for its ability to improve endothelial function. The L-arginine serves as the precursor of nitric oxide in the endothelium.
To find out if L-arginine improves arterial function in people with peripheral arterial disease, and to determine an optimal oral dose, a group of researchers from the University of California, San Francisco, analyzed the ability of L-arginine to improve the walking distance and walking speed among people with peripheral arterial disease.
A pilot study of 80 patients, given daily 3g of L-arginine daily, significantly improved both speed and walking distance.
Another study examined the effects of L-arginine in patients with stable coronary disease who were given orally. The team found that the dilation of the brachial artery, a measure of endothelial function, was improved by the application of 10 g of L-arginine.
Coenzyme Q10 is of critical importance for vascular disease, as it is directly involved in the production of adenosine triphosphate or ATP, the energy currency of the human body.
Because the heart is a muscle that never stops Do you know what would happen if it stopped? A substantial amount of Coenzyme Q10 is needed.
The levels of said nutrient in the tissue of the heartdecrease disproportionately with age. At age 20, the heart has a higher level than other important organs. At 80 years of age, there is a sudden change in levels, since the heart has levels below half of those at the age of 20.